Evidence-tiered screening
The Supplement Registry
No supplement on this page is a recommendation. These were screened for Oscar's specific stack and brought back to my oncologist. There are no purchase or affiliate links.
Read this first. Supplements can interact with chemotherapy, targeted therapy, NSAIDs, antibiotics, pain medication, bleeding risk, liver metabolism, kidney function, appetite, and stool. Natural does not mean safe. Do not copy this stack.
What was screened (Oscar)
Every supplement Oscar actually took was screened and OK’d by my oncologist before use. High-level only — not a dose schedule. Not a recommendation to copy.
| Item | Purpose | Tier | Status | Notes |
|---|---|---|---|---|
| Turkey tail / PSP-type mushroom | Immune-support adjunct idea | C/D | USED (~from May 23) | Morning stack with food. Not a TCC cure. Paused late when GI/appetite simplification mattered. OK’d by my oncologist. No buy link. |
| Avmacol / sulforaphane | Mechanistic adjunct interest | C/D | USED (nightly until trametinib) | Given every night until trametinib started (May 2026). Not a proven canine TCC therapy — adjunct only. OK’d by my oncologist. No buy link. |
| Fish oil / omega-3 | Anti-inflammatory support | D | USED (held in GI flares) | Early with Dasuquin; held some days during GI flares, then resumed with meals. Less attractive later with ulcerated lesion / bleeding concerns. OK’d by my oncologist. |
| Probiotic | Gut support during antibiotics | B/D | USED (May stack) | With food during the May stack / after GI antibiotics. Supportive care, not cancer therapy. Space from antibiotics when possible. OK’d by my oncologist. |
| Dasuquin with MSM | Joint / mobility support | B/D | USED (early) | Early-window mobility support alongside fish oil; not a cancer-control layer. OK’d by my oncologist. |
| Melatonin | Sleep / evening comfort | D | USED (evenings) | Evening supportive use in May–Jun. High-level only. OK’d by my oncologist. |
| Curcumin | Supportive adjunct | D | USED (~from Jun 5) | Owner diary “cucu” = curcumin; morning + evening from ~Jun 5. OK’d by my oncologist. |
| Quercetin | Supportive adjunct | D | USED (~from Jun 5) | Started ~Jun 5 mornings with curcumin. OK’d by my oncologist. |
| Food support (pumpkin, cooked beef, cheese, etc.) | Appetite & stool comfort | D | USED (with holds) | Practical care. Green beans stopped when dark stool was suspected. Later, stool bulk also mattered for the perianal lesion. |
| Saline / gentle wound care | Lesion cleanliness | Wound care | Later / wound phase | Cannot “heal” a metastatic tumor wound. Avoid alcohol/peroxide. |
Confirmed used under oncologist OK: turkey tail, Avmacol, fish oil, probiotic, Dasuquin, melatonin, curcumin, quercetin. Denamarin was never started. GI holds (piroxicam pause, fish oil holds, green beans stopped when dark stool suspected) were part of the monitoring loop.
What we rejected
- Alcohol wipes on the open lesion
- Hydrogen peroxide on the crater
- Hot-spot / anti-itch / pain sprays near the open crater
- Ivermectin as last-chance cancer therapy
- Stacking every plausible supplement at once
- Denamarin — considered earlier, but never started
- Unconfirmed items from other dogs' records (e.g. Yunnan Baiyao / tranexamic acid) unless confirmed for Oscar
The screening method
- Define purpose
- Identify mechanism
- Check current drug stack
- Check organ-risk overlap
- Check bleeding / GI / appetite risk
- Assign evidence tier
- Compress into a one-page oncologist question
- Add one thing at a time only if approved
- Re-measure with labs and observation
The transferable lesson is not the supplement list. It is the screening method.
Related: prompt pack · method